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Julien Hamelet Selected Research

Cystathionine beta-Synthase (Serine Sulfhydrase)

8/2009Effects of red wine polyphenolic compounds on paraoxonase-1 and lectin-like oxidized low-density lipoprotein receptor-1 in hyperhomocysteinemic mice.
6/2009Calpain activation is required for homocysteine-mediated hepatic degradation of inhibitor I kappa B alpha.
1/2009Effect of hyperhomocysteinemia on the protein kinase DYRK1A in liver of mice.
1/2009Resveratrol supplementation worsen the dysregulation of genes involved in hepatic lipid homeostasis observed in hyperhomocysteinemic mice.
7/2008Cystathionine beta synthase deficiency induces catalase-mediated hydrogen peroxide detoxification in mice liver.
10/2007Mice lacking cystathionine beta synthase have lung fibrosis and air space enlargement.
8/2007Mice deficient in cystathionine beta synthase display altered homocysteine remethylation pathway.
3/2007Effects of catechin on homocysteine metabolism in hyperhomocysteinemic mice.
1/2007Hyperhomocysteinemia due to cystathionine beta synthase deficiency induces dysregulation of genes involved in hepatic lipid homeostasis in mice.
8/2006Paraoxonase-1 expression is up-regulated in Down syndrome fetal liver.

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Julien Hamelet Research Topics

Disease

9Hyperhomocysteinemia
08/2009 - 08/2006
8Homocystinuria
08/2009 - 08/2006
4Fibrosis (Cirrhosis)
01/2014 - 10/2007
1Hypertrophy
01/2014
1Metabolic Syndrome (Dysmetabolic Syndrome X)
07/2013
1Thrombosis (Thrombus)
08/2009
1Atherosclerosis
08/2009
1Inflammation (Inflammations)
06/2009
1Liver Diseases (Liver Disease)
01/2009
1Fatty Liver
01/2007
1Vascular Diseases (Vascular Disease)
08/2006
1Down Syndrome (Down's Syndrome)
08/2006

Drug/Important Bio-Agent (IBA)

10Cystathionine beta-Synthase (Serine Sulfhydrase)IBA
08/2009 - 08/2006
3Aryldialkylphosphatase (Paraoxonase)IBA
08/2009 - 08/2006
3HomocysteineIBA
08/2009 - 03/2007
2Oxidoreductases (Dehydrogenase)IBA
07/2013 - 08/2007
2FlavonoidsIBA
08/2009 - 03/2007
2Methionine (L-Methionine)FDA Link
08/2009 - 01/2009
2CalpainIBA
06/2009 - 01/2009
2Proteins (Proteins, Gene)FDA Link
01/2009 - 01/2007
2Catechin (Z 7300)IBA
01/2009 - 03/2007
2CholesterolIBA
07/2008 - 01/2007
2EnzymesIBA
08/2007 - 01/2007
1Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA
01/2014
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2014
1Phenylephrine (Neo-Synephrine)FDA LinkGeneric
01/2014
1Small Interfering RNA (siRNA)IBA
07/2013
1AMP-Activated Protein KinasesIBA
07/2013
1Drinking WaterIBA
08/2009
1Biological ProductsIBA
08/2009
1Biomarkers (Surrogate Marker)IBA
08/2009
1Protein Kinases (Protein Kinase)IBA
01/2009
1Sulfhydryl Compounds (Thiols)IBA
01/2009
1PolyphenolsIBA
01/2009
1Amino AcidsFDA Link
01/2009
1ResveratrolIBA
01/2009
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
07/2008
1Glutathione Transferase (Glutathione S-Transferase)IBA
07/2008
1Glutathione Reductase (Glutathione-Disulfide Reductase)IBA
07/2008
1Glutathione PeroxidaseIBA
07/2008
1NADPH Oxidases (NAD(P)H oxidase)IBA
07/2008
1CatalaseIBA
07/2008
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2007
1Interleukin-6 (Interleukin 6)IBA
10/2007
1CytokinesIBA
10/2007
1alpha 1 Chain Collagen Type IIBA
10/2007
1Heme Oxygenase-1IBA
10/2007
1Transforming Growth Factor beta1 (TGF beta 1)IBA
10/2007
1Betaine-Homocysteine S-Methyltransferase (Betaine Homocysteine Methyltransferase)IBA
08/2007
15-Methyltetrahydrofolate-Homocysteine S-Methyltransferase (Methyltetrahydrofolate Homocysteine Methyltransferase)IBA
08/2007
15,6,7,8-tetrahydrofolic acid (tetrahydrofolate)IBA
08/2007
1QuercetinIBA
03/2007
1Scavenger Receptors (Scavenger Receptor)IBA
01/2007
1Fatty Acids (Saturated Fatty Acids)IBA
01/2007
1LipidsIBA
01/2007
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
08/2006